Publications

PI's Publications

In collaboration and primary research

Protein neddylation as a therapeutic target in pulmonary and extrapulmonary small cell carcinomas

Justin P. Norton, Arnaud Augert, Emily Eastwood, Ryan Basom, Charles M. Rudin, David MacPherson

Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition

Deshui Jia*, Arnaud Augert*, Dong-Wook Kim*, Emily Eastwood, Nan Wu, Ali H. Ibrahim, Kee-Beom Kim, Colin T. Dunn, Smitha P.S. Pillai, Adi F. Gazdar, Hamid Bolouri, Kwon-Sik Park, David MacPherson

*co-first author

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence

Clotilde Wiel*, Hélène Lallet-Daher*, Delphine Gitenay, Baptiste Gras, Benjamin Le Calvé, Arnaud Augert, Mylène Ferrand, Natalia Prevarskaya, Hélène Simonnet, David Vindrieux, David Bernard

*co-first author

MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer

Arnaud Augert, Haritha Mathsyaraja, Ali H. Ibrahim, Brian Freie, Michael J. Geuenich, Pei-Feng Cheng, Sydney P. Alibeckoff, Nan Wu, Joseph B. Hiatt, Ryan Bakom, Adi Gazdar, Lucas B. Sullivan, Robert N. Eisenman, David MacPherson

Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance)

Arnaud Augert, Qing Zhang, Breanna Bates, Min Cui, Xiaofei Wang, Gary Wildey, Afshin Dowlati, David MacPherson

PTEN Is a Potent Suppressor of Small Cell Lung Cancer

Min Cui, Arnaud Augert, Michael Rongione, Karina Conkrite, Susan Parazzoli, Alexander Yu. Nikitin, Nicholas Ingolia, David MacPherson

Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis

C Wiel, A Augert, D F Vincent, D Gitenay, D Vindrieux, B Le Calvé, V Arfi, H Lallet-Daher, C Reynaud, I Treilleux, L Bartholin, E Lelievre, D Bernard

NUAK1 links genomic instability and senescence

David Bernard, Arnaud Augert

The M-type receptor PLA2R regulates senescence through the p53 pathway

Arnaud Augert, Christine Payré, Yvan de Launoit, Jesus Gil, Gérard Lambeau, David Bernard

Platelet-derived growth factor B induces senescence and transformation in normal human fibroblasts

David Vindrieux, Baptiste Gras, Merce Garcia-Belinchon, Samia Mourah,Céleste Lebbe, Arnaud Augert, David Bernard

A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence

Nicolas Humbert, Sébastien Martien, Arnaud Augert, Marco Da Costa, Sébastien Mauen, Corinne Abbadie, Yvan de Launoit, Jesús Gil, David Bernard

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

Juan C. Acosta*, Ana O'Loghlen*, Ana Banito, Maria V. Guijarro, Arnaud Augert, Selina Raguz, Marzia Fumagalli, Marco Da Costa, Celia Brown, Nikolay Popov, Yoshihiro Takatsu, Jonathan Melamed, Fabrizio d'Adda di Fagagna, David Bernard, Eva Hernando, Jesús Gil

*co-first author

Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition

Arnaud Augert*, Emily Eastwood*, Ali H. Ibrahim, Nan Wu, Eli Grubblat, Ryan Bakom, Denny Ligist, Keith D. Eaton, Renato Martins, John T. Poirier, Charles M. Rudin, Francesca Milletti, Wei-Yi Cheng, Fiona Mack, David MacPherson

*co-first author

Treating Transcriptional Addiction in Small Cell Lung Cancer

Arnaud Augert, David MacPherson

PLA2R1 Mediates Tumor Suppression by Activating JAK2

David Vindrieux*, Arnaud Augert*,

Christophe A. Girard, Delphine Gitenay, Helene Lallet-Daher, Clotilde Wiel, Benjamin Le Calvé, Baptiste Gras, Mylène Ferrand, Stéphanie Verbeke, Yvan de Launoit, Xavier Leroy, Alain Puisieux, Sébastien Aubert, Michael Perrais, Michael Gelb, Hélène Simonnet, Gérard Lambeau, David Bernard

*co-first author

PLA2R1 kills cancer cells by inducing mitochondrial stress

Arnaud Augert, David Vindrieux, Christophe A. Girard, Benjamin Le Calvé, Baptiste Gras, Mylène Ferrand, Benjamin P. Bouchet, Alain Puisieux, Yvande Launoite, Hélène Simonnet, Gérard Lambeau, David Bernard

Regulation of ploidy and senescence by the AMPK-related kinase NUAK1

Nicolas Humbert*, Naveenan Navaratnam*, Arnaud Augert, Marco Da Costa, Sébastien Martien, Jing Wang, Dolores Martinez, Corinne Abbadie, David Carling, Yvan de Launoit, Jesus Gil, David Bernard

*co-first author